There are multiple definitions:
thorium(English)
Th cell(English)
- plays a key role in the adaptive immune system by coordinating effector functions leading to destructive responses, including pathogen clearance as well as autoimmunity. Initially defined as distinct into two major subsets, based on the type of cytokines they produce, Th cell differentiation is also driven by cytokines and specific type of antigens, that in synergy, trigger unique transcription factors which become lineage specification markers. The well-characterized Th1 and Th2 subsets produce IFN-? and IL-12 or IL-4, IL-5, and IL-13 and are important for responses against intracellular microbes and parasites, respectively. New knowledge in epigenetic posttranscriptional regulators added more complexity to the effector arm of the adaptive immune system, adjusting to the environment
- Autoimmunity, Epigenetics, Environment, Parasitology
- https://doi.org…74279-7.18008-7