PHD

There are multiple definitions:

  1. plant homeodomain(English)

  2. pulmonary heart disease(English)

  3. prolyl hydroxylase domain-containing protein(English)

  4. prolyl 4-hydroxylase domain(English)

    • the concentration of cytosolic oxygen is sensed by these proteins that act on HIF-1α. Under normoxia, they hydroxylate two highly conserved proline residues (Pro402 and Pro564) located within the oxygen-dependent degradation domain. There are three isoforms
    • HIF-1α, pVHL, ODDD
    • Oxygen
    • https://doi.org…409231003627991