pheochromocytoma or paraganglioma(English)

• rare neuroendocrine tumors arising from chromaffin cells of the adrenal medulla and the extra-adrenal neural crest progenitors, respectively, both of which may secrete catecholamines. The estimated annual incidence is 0.8 per 100,000 person-years. As clinical presentation is widely variable and nonspecific, diagnosing can be extremely challenging. Some patients present with the classic triad, which consists of episodic headache, diaphoresis, and tachycardia, while others present with sustained or paroxysmal hypertension or with local tumor symptoms such as abdominal pain, or are asymptomatic. A crisis is defined as an acute severe presentation of catecholamine-induced hemodynamic instability causing end-organ damage or dysfunction
• Endocrinology, Neuropathy, Oncology, Emergency medicine, Diagnostics
• https://doi.org…000-021-00274-6