CpG [islands]

cytosine nucleotide proximal to a guanine nucleotide(English)

  • regions of DNA enriched with methylated cytosine residues adjacent to guanine nucleotides which serve as docking sites for methyl-binding proteins that, along with other protein complexes, remodel and condense chromatin. Thus, CpG methylation inhibits the transcription of the nearby genes by condensing chromatin and blocking its accessibility to various transcription factors
  • DNA, TET
  • Epigenetics
  • https://doi.org…3-319-77932-4_2