chronic kidney disease(English)
- affects >10% of the world population, with increasing prevalence in middle age. The risk is dependent on the number of functioning nephrons through the life cycle, and 50% of nephrons are lost through normal aging, revealing their vulnerability to internal and external stressors. As defined by an eGFR less than 60 mL/min/1.73 m2, is found in up to 40% to 60% of patients with HFpEF, partially due to multiple common underlying comorbidities
- AKI, BMDM, CKDmfo, CKDu, CRP, DOCA, eGFR, Gal-1, GFR, HFpEF, HOMA-ß, HTN, IFN-γ, IL-6, iNOS, LVEF, M-CSF, MI, NKF, NPX, PTWI, RAAS, SIRT-1, UACR, UPR
- Nephrology, Therapeutic approaches, Aging, Injury, Mitochondrion, Bioenergetics, Cardiology
- https://doi.org…srev.00029.2022
- https://doi.org…ere.2020.125836
- https://doi.org…cna.2025.04.006
- https://doi.org…ONAHA.125.26006