COSMIC

Catalogue Of Somatic Mutations In Cancer(English)

  • the most detailed and comprehensive resource for exploring the effect of somatic mutations in human cancer. The August 2018 release includes almost 6 million coding mutations across 1.4 million tumor samples, curated from over 26 000 publications. Also covers all the genetic mechanisms by which somatic mutations promote cancer, including non-coding mutations, gene fusions, copy-number variants and drug-resistance mutations. New functionality allows exploration of mutations within three-dimensional protein structures, their protein structural and functional impacts, and implications for druggability
  • CGC, ICGC, TCGA
  • Oncology, Medical informatics, Classification
  • https://cancer.…er.ac.uk/cosmic
  • https://doi.org…093/nar/gky1015