chronic kidney disease(English)
- affects >10% of the world population, with increasing prevalence in middle age. The risk is dependent on the number of functioning nephrons through the life cycle, and 50% of nephrons are lost through normal aging, revealing their vulnerability to internal and external stressors. As defined by an eGFR less than 60 mL/min/1.73 m2, is found in up to 40% to 60% of patients with HFpEF, partially due to multiple common underlying comorbidities
- NKF, MI, AKI, HOMA-ß, GFR, eGFR, RAAS, UPR, SIRT-1, PTWI, CKDmfo, CKDu, UACR, HFpEF
- Nephrology, Therapeutic approaches, Aging, Injury, Mitochondrion, Bioenergetics, Cardiology
- https://doi.org…srev.00029.2022
- https://doi.org…ere.2020.125836
- https://doi.org…cna.2025.04.006