There are multiple definitions:

1. volume of interest(English)

   • MRI, ROI
   • Medical imaging
   • https://doi.org…umed.117.194373

2. variant of interest(English)

   • evidence is available on genomic properties, epidemiological evidence or in-vitro evidence that could imply a significant impact on transmissibility, severity and/or immunity, realistically having an impact on the epidemiological situation
   • COVID-19, VOC, WHO
   • Virology, Epidemiology
   • https://www.ecd…n in the EU/EEA