tumor necrosis factor alpha(English)

• initially recognized as a factor that causes the necrosis of tumors, but it has been recently identified to have additional important functions as a pathological component of autoimmune diseases. A cytokine that has pleiotropic effects on various cell types. It has been identified as a major regulator of inflammatory responses and is known to be involved in the pathogenesis of some inflammatory and autoimmune disease
• CIMT, EC, eNOS, HAT1, hs-CRP, IGF, KLF, LPS, MCP-1, MMP, NF-kB, SIRT1, SOCS1, TLR4, VCAM-1, VSMC, VEGF
• Autoimmunity, Pathology
• https://doi.org…0/ijms232415645
• https://10.3390/ijms22052719