triple knockout [mouse](English)

• in this variant autophagy is greatly suppressed compared with DKO mice. Embryonic fibroblasts and thymocytes from TKO mice undergo autophagy much less frequently, and their viability is much higher than DKO cells in the presence of certain cellular stressors, providing genetic evidence that DKO cells undergo Atg5-dependent death
• KO, DKO
• Transgenic animal, Experimental animal, Apoptosis
• https://doi.org…038/cdd.2017.84