T cell protein tyrosine phosphatase(English)
- protected against intestinal barrier dysfunction induced by the inflammatory cytokine IFN-γ by 2 mechanisms: it maintained localization of zonula occludens 1 and occludin at apical tight junctions and restricted both expression and insertion of the cation pore-forming transmembrane protein, claudin-2, at tight junctions through upregulation of the inhibitory cysteine protease, matriptase
- ADX, ARC, CART, ERK1/2, IRS, JNK, NPY, PTP1B, IBD, IFN-γ
- Insulin, Gastroenterology
- https://doi.org…530/joe-19-0217
- https://doi.org….1172/jci138230