monocarboxylate ketone transporter(English)
- belongs to the solute carrier family (SLC16), transporting molecules like lactate, pyruvate, and ketone bodies across cell membranes. Mutations in SLC16A1 (encoding MCT1) impair extrahepatic ketone utilization, leading to recurrent, profound ketoacidosis during fasting or infections
- BDK, CD36, CD38, CK, CoA, CPT-1, DNMT3A, Drp1, ERK, FADH2, FATP-1, Fis1, FOXM1, G6P, GCGR, GLUT1, GLUT4, HBP, LIVCS, MCD, Mfn1, MPC, mTOR, NADPH, NAMPT, NMNAT, NRF-1, NRK, PARP, PKM, SCOT, Sirt3, TCA, MCT1, SLC, ACC, AMPK, BCAA, BCATm, BCKA, BCKDH
- Metabolism, Mitochondrion, Cardiology
- https://doi.org…SAHA.121.318241