PPNAD

primary pigmented nodular adrenocortical disease(English)

  • a rare cause of childhood Cushing’s disease having female preponderance, whereas Cushing’s disease is common in prepubertal males. It is the main endocrine manifestation of Carney complex (a multiple neoplasia syndrome caused by mutation in PRKAR1A gene). This is an autosomal dominant syndrome and is characterized by cutaneous lentigines, myxoma, schwannomas, and endocrinopathy
  • ACTH
  • Endocrinology, Cortisol
  • https://doi.org…ntechopen.84815