pNFPA

postoperative nonfunctioning pituitary adenoma(English)

  • primary treatment of NFPA is pituitary microsurgery with transsphenoidal or transcranial approach to achieve a rapid reduction of tumor volume and decompression of the optic apparatus. Significant tumor debulking improves visual field disorders in 80% of patients and relieves headaches in almost every case. However, during long-term follow-up after transsphenoidal surgery, there is tumor regrowth in 12–46% of the patients. Medical therapy with dopamine agonists or somatostatin analogs has a variable and often limited impact on the risk of recurrence. Cases with or without detectable residual tumor, need stratification of treatment and radiological / endocrinological follow-up strategy. According to the TVDT, residual tumor regrowth is very slow, which permits an extensive and safe follow-up program for most patients
  • NFPA, TVDT
  • Pituitary (gland), Surgery
  • https://doi.org….1159/000339823