PIPO

pediatric intestinal pseudo-obstruction(English)

  • a rare and debilitating clinical disorder characterized by the chronic inability of the gastrointestinal tract to propel its contents via mimicking mechanical obstruction, in the absence of a lesion that might occlude the gut. Chronic is defined as the persistence of symptoms that lasts for 2 months, starting from birth or at least 6 months after. The diagnosis requires at least 2 out of 4 of the following: an objective measurement of the small intestinal neuromuscular involvement (manometry, histopathology, transit); recurrent and/or persistently dilated loops of small intestine with air-fluid levels; genetic and/or metabolic abnormalities definitively associated with PIPO; and the inability to maintain adequate nutrition and/or growth with oral feeding (needing a special enteral nutrition and/or parenteral nutrition support)
  • ADM, CIPO, GE, GES
  • Pediatrics, Gastroenterology, Nutrition
  • https://doi.org…/tjg.2019.18287