There are multiple definitions:
polyglactin-910(English)
paraganglioma(English)
- tumor that arises in extra-adrenal sympathetic chromaffin tissue or head and neck parasympathetic tissues. Associated syndromes types 1–5 are autosomal dominant, characterized by familial predisposition to PGL, pheochromocytoma (PC), renal cell cancers, gastrointestinal stromal tumors and, rarely, pituitary adenomas. Each syndrome is associated with mutation in a gene encoding a particular subunit (or assembly factor) of succinate dehydrogenase (SDHx). The clinical manifestations of these syndromes are protean: patients may present with features of catecholamine excess (including the classic triad of headache, sweating and palpitations), or with symptoms from local tumor mass, or increasingly as an incidental finding on imaging performed for some other purpose. Genetic testing permits presymptomatic diagnosis, although penetrance of disease in these syndromes is highly variable and tumor development does not clearly follow a predetermined pattern
- SDHx, PC
- Oncology
- https://doi.org…530/ERC-15-0268
persistent generalized lymphadenopathy(English)
- defined as enlarged lymph nodes involving at least two noncontiguous sites, other than inguinal nodes, persisting for more than 3 months
- Physical examination, Dermatology
- https://doi.org…06790-7.50015-6