long-acting injectable formulation(English)

• received substantial attention recently due to their advantages over conventional formulations, including easy administration, continuous and controlled release of drug over months, and the ability to maintain drug concentrations within the therapeutic range. The constant advances in biotechnology produce complex active pharmaceuticals that might be difficult to administer by conventional means. In particular, peptides, proteins, and antibodies are hard to administer orally given their physicochemical instability in the gastrointestinal tract and short half lives in blood. Therefore, they are good candidate delivery systems for such drugs, and reduce the frequency of application and improve patient compliance. For instance, LAIF-based antipsychotics can be more effective in patients with bipolar disorder and schizoaffective disorder
• BPD, SAD, LAR
• Psychiatry, Therapeutic approaches, Pharmacology / pharmaceutics
• https://doi.org…005-019-00449-9