There are multiple definitions:

1. intermediate filament associated protein(English)

   • protein that binds to intermediate filaments (IFs), linking them to other cell structures like membranes (desmosomes, hemidesmosomes), organelles, and other cytoskeletal elements, crucial for cell structure, migration, and signaling. Key examples include Filaggrin (aggregates keratin in skin), GFAP (Glial Fibrillary Acidic Protein) (in astrocytes), and various size-specific proteins like IFAP-300kDa (binds vimentin in developing CNS/tumors) or the 48-kDa IFAP, helping create functional networks for mechanical support and cellular processes
   • IF, GFAP
   • Biochemistry, Proteins / proteomics, Dermatology, Cell biology
   • https://doi.org…3233(05)70006-1
   • https://link.sp…94-011-9702-1_7

2. Ichthyosis Follicularis, Alopecia, and Photophobia [syndrome](English)

   • type 2 is a condition that has been linked to a c.1579C>T mutation in the SREBF1 gene. However, the molecular implications of the mutation in Meibomian glands (MG) remain unknown
   • MG, LDLR, SREBP1, SRE, MBTPS2
   • Dermatology, Congenital disorders, Ophthalmology, Gland(ular), Transcription
   • https://doi.org…xer.2025.110703
   • https://doi.org…jhg.2020.05.006