Western Equine Encephalitis Virus(English)

• human infections range from inapparent (the vast majority) to a flu-like syndrome to life-threatening encephalitis and meningitis. Symptomatic infection typically includes a sudden onset with fever, headache, nausea, vomiting, anorexia, and malaise, followed by cognitive symptoms, weakness, and meningeal involvement. Young children tend to be affected more severely than adults, and 5–30% suffer permanent neurologic sequelae. The overall human case–fatality rate is about 3%. WEEV also causes encephalitis in equids, with case–fatality rates of 10–50%. Despite a history of producing epidemics with thousands of human cases, WEEV has apparently declined as a human pathogen since the 1970s, probably due in part to irrigation, mosquito control, and culturally reduced human exposure to mosquitoes
• EEEV, SINV, WEE
• Virology, Brain (dys)function
• https://doi.org…74410-4.00627-0