There are multiple definitions:

1. worst case imputation(English)

   • substitution of missing data with the value that represents the worst possible outcome
   • BP, CCA, LOCF, MI, MI-B, MI-BP, MM, mRS, NINDS, tPA
   • Statistics, Model(ing)
   • https://doi.org…dis.2018.08.040
   • https://doi.org…2874-017-0442-1

2. whole cell phase I(English)

   • natural antigen, often derived from Coxiella burnetii in Q fever studies. Refers to laboratory-adapted, cultivated bacteria used for serodiagnosis or vaccine testing
   • CMR, FIA, IFA, WCII, WCV
   • Diagnostics, Vaccination
   • http://pubmed.n…ih.gov/8134661/