immune stimulating complex(English)
- composed of a matrix containing Quillaja saponins, cholesterol and phospholipid at a molar ratio of about 1:1:1. The assembly is facilitated by hydrophobic interaction between these components and the antigen which may be an envelope protein of a native virus, a cellular membrane protein, or peptides containing hydrophobic domains or any antigen with a hydrophobic domain. In the case of virus, the envelope is disintegrated by a detergent, preferably nonionic, to release a protein–detergent complex
- HIV
- Immunology
- https://doi.org…/rwei.1999.0385