IGD

There are multiple definitions:

  1. internet gaming disorder(English)

  2. isolated GnRH deficiency(English)

    • pertains to a group of genetic disorders consisting of anosmic hypogonadotropic hypogonadism (e.g. KS) and normosmic idiopathic hypogonadotropic hypogonadism (nIHH). It is a rare disorder with an estimated incidence of 1/48,000 births. It is caused by a defect in the HPG axis, resulting in low levels of sex steroids and a delay or absence of puberty. Divided into anosmic hypogonadotropic hypogonadism (Kallmann syndrome, KS) and normosmic idiopathic hypogonadotropic hypogonadism (nIHH). About 60% of patients with IGD present with anosmia or hyposmia (KS) by total or partial defects of the olfactory bulb due to the fact that the GnRH-releasing neurons are primarily derived from progenitor cells in the nasal compartment and migrate along the fibers derived from the olfactory system across the cribriform plate to the forebrain
    • GnRH, HPG, KS, nIHH
    • Genitals, Olfactory system
    • https://doi.org…ene.2015.12.001