There are multiple definitions:

1. hypoxic ventilatory drive(English)

   • COPD, HPV
   • Pulmonology

2. highly variable drug(English)

   • the estimated within-subject variability is >30%, and therefore they often fail to meet current regulatory acceptance criteria for average bioequivalence
   • ABE, FDA, SABE
   • Pharmacology / pharmaceutics, Standards

3. high-voltage device(English)

   • ICD, CRT-D, VA
   • Cardiology, Electrophysiology
   • https://doi.org…ircj.cj-23-0801