4-hydroxynonenal(English)

• decreases mitochondrial oxygen consumption by inhibiting electron transport chain complexes. Metabolic, mitochondrial, sarcomeric, and cytoskeletal proteins are susceptible to 4HNE-adduction in patients with RV failure. A byproduct of lipid peroxidation; aka 4HNE
• RV, TOF
• Mitochondrion, Cardiology, Oxygen, Bioenergetics
• https://doi.org…NAHA.120.045470