head and neck cancer(English)

• includes cancers in oral cavity, pharynx, and larynx. Earlier case-control studies suggested that obesity was inversely related to the risk of head and neck cancer, particularly among smokers and alcohol drinkers. Given that smoking is a strong risk factor, and smokers tend to have lower BMI than nonsmokers, the inverse association observed in smokers suggested residual confounding (i.e., incomplete adjustment) by smoking. Later, a large pooled analysis of 20 prospective cohort studies found that every five unit increase in BMI was associated with 15% increased risk in never smokers. In addition, abdominal obesity assessed by waist circumference was related to a higher risk of head and neck cancer in never and former smokers
• BMI, OPSCC, NPC, CCRT, GA, fTRST, mFI-5, QOL, TRST
• Oncology, Mouth, esophagus and stomach, Adiposity, Frailty
• https://doi.org…01238-3.65037-7
• https://doi.org…ogy.2023.106621