hypoxia-inducible factor(English)

• a particular transcription factor; hypoxia‐induced reprogramming of metabolism is key to satisfying cellular energetic requirements during acute hypoxic stress. At a transcriptional level, this metabolic switch can be regulated by several pathways including the hypoxia inducible factor‐1α which induces an increased expression of glycolytic enzymes
• HIF‐1α, FIH, HDAC4, HIF-2α, HIF-1
• Bioenergetics, Metabolism, Transcription, Oxygen
• https://doi.org/10.1113/JP280572