Hutchinson–Gilford progeria syndrome(English)

• the LMNA c.1824C→T mutation disrupts the normal splicing pattern of LMNA messenger RNA, which results in the production of a shorter lamin A protein; this mutant protein is called progerin in reference to the disease
• LMNA, mRNA
• Congenital disorders, Aging
• https://doi.org…NEJMcibr2100661
• https://doi.org…emed.2021.00041
• https://doi.org…422-024-00977-6