DREADD

designer receptors exclusively activated by designer drug(English)

  • a class of chemogenetically engineered proteins that can activate a receptor. To understand brain function, it is essential to discover how cellular signaling specifies normal and pathological brain function. In this regard, chemogenetic technologies represent valuable platforms for manipulating neuronal and non-neuronal signal transduction in a cell-type-specific fashion. These chemogenetic tools are now commonly used by neuroscientists to identify the circuitry and cellular signals that specify behavior, perceptions, emotions, innate drives, and motor functions
  • RASSL
  • Signal transduction, Receptors
  • https://doi.org…ron.2016.01.040