disruptor of telomeric silencing 1-like(English)

• a histone H3K79 methyltransferase that plays a key role in transcriptional elongation and cell cycle regulation and is required for the development and maintenance of MLL-rearranged mixed lineage leukemia
• HOXA9, HSC, JARID2, JmjC, IDH1, IDH2, MM, MDS, MLL, MPN, MEIS1, NPM1, PRC2, SAM, SDH, TCA, TET, α-KG, 2-HG, 5hmC, 5mC, AML, ASXL1, AZA, CMML, DAC, DNMT3A, DNMTi, EZH2, FH, HDAC, HDACi
• Leukemia, Biochemistry, Translational research
• https://pubs.ac…medchem.6b01785
• https://doi.org…rsl.2014.04.012