dengue virus(English)

• a mosquito-borne member of the Flavivirus genus that includes four serotypes, each of which is capable of causing dengue fever and dengue hemorrhagic fever/dengue shock syndrome. Serious disease can be seen during primary infection but is more frequent following second infection with a serotype different from that of a previous infection. Infection with wild-type DENV induces high-titered neutralizing antibody that can provide long-term immunity to the homotypic virus and can provide short-term immunity (only several months duration) to a heterotypic DENV. Vaccines need to provide long-term protection against each of the four DENV serotypes by inducing neutralizing antibodies
• USUV, WNV, ZIKV, JEV
• Virology, Vaccination, Infection
• https://doi.org…l-031210-101315
• https://doi.org…1564-020-0714-0