DExD/H-box helicase 58(English)

• putative RNA helicase implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral dsRNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. Also known as RIG1; RIG-I; RLR-1; SGMRT2
• CARD, dsRNA
• Genetics, Regulation / control, Spleen, Immunology
• https://www.ncb….gov/gene/23586
• https://doi.org….1002/ejhf.2534