dinucleotide-based auto-cross covariance(English)

• applied to recombination hot/cold spots identifcation, which is able to incorporate the global sequence-order effects in the DNA sequences into the predictor. Combined with Support Vector Machines, a predictor called iRSpot-DACC is proposed. In order to further improve its performance and computational cost, Principal Component Analysis is adopted
• DAC, DCC, PCA, SVM
• Genomics, Epigenetics
• https://doi.org….1038/srep33483