AKAP6β

A-kinase anchoring protein 6β(English)

  • a 230 kDa scaffold protein, in cardiomyocytes localized to the nuclear envelope. Required for primary ventricular myocyte hypertrophy in vitro and the induction of pathological cardiac remodeling and heart failure by isoproterenol infusion, chronic pressure overload, and myocardial infarction in vivo. Also known as mAKAPβ
  • FHA1, FRET, GPCR, ICL3-9, NFAT, OCT3, ONM, PKA, AKAP, BAR, cAMP
  • Cardiology, Myocyte / muscle
  • https://doi.org…NAHA.124.072682