STimulator of INterferon Gene(English)

• an adaptor molecule in the cytosolic DNA-sensing pathway, which has emerged as a central player in antiviral and antibacterial immunity, autoinflammation, and cancer. An endoplasmic reticulum–associated membrane protein expressed in a wide variety of tissues, including endothelial, epithelial, and hematopoietic cell types. Signaling through STING can be induced by cyclic di-GMP, cyclic di-AMP, and cGAMP
• TANK, TBK1, AMP, cGAS, ER, GMP, ISG, cGAMP, CDN
• Immunology, Oncology, Infection
• https://doi.org…aci.2018.04.034
• https://doi.org…6/NEJMra2206346