There are multiple definitions:
small acid soluble protein(English)
- refers to spore
- TARP, TTSS
- https://doi.org…01238-3.02310-2
senescence-associated secretory phenotype(English)
- a distinct secretory phenotype of senescent cells including those generated by the side effect of chemotherapy and radiation, can unintendedly, but significantly promote drug resistance, local inflammation, and tumor metastasis by enforcing the secretion of cells that survive treatments. As a full senescence response is indeed not required for the SASP, a phenomenon mainly observed upon genotoxic stimuli, the DNA damage secretory program (DDSP) is probably more appropriate to depict the mechanism responsible for a typical SASP. Expression of soluble factors in the full SASP spectrum not only induces an epithelial to mesenchymal transition (EMT), but also creates an immunosuppressive milieu, thereby driving tumorigenesis and shaping tumor resistance against multiple types of anticancer agents
- ATM, DDSP, DNA, EMT, TAK1, HUVEC, TRAF6, SCAP, SAMD, BRAF
- Aging, Genetics, Oncology, Pharmacology / pharmaceutics, Chemotherapy
- https://doi.org…467-018-04010-4
- https://doi.org…iom.2017.04.013
- https://doi.org…l-121808-102144