myeloid-derived growth factor(English)

• produced by monocytes and macrophages. It mediates crosstalk between bone marrow and the heart. Inhibits cardiac hypertrophy and augments SERCA2a to attenuate pressure-overload induced heart failure. Induces cardiomyocyte proliferation to improve postinfarction cardiac function. Silencing and upregulation modulate exacerbates podocyte survival in nephropathy
• OTUB1, Pp2a, RBP2, SERCA2a, SGLT2i, SNCA, TBCA, TFF1, TfR1, UMOD, UMtCK, UROD, ACYP1, ATPIFI, CA2, CCL5, CCL28, CDHR2, CELSR2, CgA, CST1, DNAJB1, DNAJC9, eGFR, EPCAM, EPO, ERMAP, ESCRT-III, FABP5, FABP6, FDRq, HSPA8, H-FABP, IGBP1, IGF1, IGFBP-1, IST1, KYAT1, L-FABP, MMRM, NHE3
• Cardiology, Kidney and adrenals, Biomarker, Cell biology
• https://doi.org…acc.2024.07.013