microbial small RNA(English)
- is enriched on low-density lipoprotein and drives pro-inflammatory macrophage polarization and cytokine secretion via activation of the RNA sensor toll-like receptor 8 (TLR8). Removal of msRNA cargo during LDL re-constitution yields particles that readily promote sterol loading but fail to stimulate inflammatory activation
- TLR8, APOB, LDL, nLDL, rLDL, sRNA
- Atherosclerosis /atherogenic, Clinical chemistry
- https://doi.org…556-022-01030-7