mosaic loss of chromosome Y [in the blood](English)

• a condition in which a fraction of hematopoietic cells display a loss of the Y chromosome. This phenomenon is the most prevalent post-zygotic mutation in leukocytes. The frequency of hematopoietic mLOY increases with age and smoking status, and is associated with the condition of clonal hematopoiesis of indeterminate potential
• SMAD2, BMT, CHIP, FISH
• Cardiology, Aging, Gender aspects, Epigenetics
• https://doi.org…science.abn3100