There are multiple definitions:

1. major depressive episode(English)

   • Depression

2. myocardial delay enhancement(English)

   • CMR, DCM
   • Cardiology, Medical imaging

3. myeloma-defining event(English)

   • the diagnosis of MM requires the presence of one or more of these events in addition to evidence of either 10% or more clonal plasma cells on bone marrow examination or a biopsy-proven plasmacytoma. MDE consists of established CRAB features (hypercalcemia, renal failure, anemia, or lytic bone lesions) and 3 specific biomarkers
   • CRAB, FLC, MM, MRD, MRI
   • Hematology, Oncology
   • https://doi.org/10.1002/hon.2586