GM130

Golgi matrix protein 130(English)

  • a protein of 130 kD, the COOH-terminal domain of which is highly homologous to a Golgi human auto-antigen, golgin-95. Biochemical data show that this is a peripheral cytoplasmic protein that is tightly bound to Golgi membranes and part of a larger oligomeric complex. Predictions from the protein sequence suggest that GM130 is an extended rod-like protein with coiled-coil domains. Immunofluorescence microscopy showed partial overlap with medial- and trans-Golgi markers but almost complete overlap with the cis-Golgi network marker, syntaxin
  • CGN, ER
  • Proteins
  • https://doi.org…/jcb.131.6.1715