growth differentiation factor 15(English)

• an appetite-regulating hormone with a brainstem-restricted receptor, the GDNF family receptor α-like (GFRAL). An increased level of this factor is strongly associated with an increased composite risk of all-cause mortality and heart failure hospitalization after admission for acute heart failure, independent of multiple biomarkers including NT-proBNP. Has also been demonstrated as a promising prognostic marker, specifically for HFrEF. Is the most important protein used to distinguish three HFrEF phenogroups. Also denoted as GDF15
• HF, NT-proBNP, GFRAL, ARNI, EDV, eGFR, HFrEF, HHF, HIC, KCCQ-OS, LVEF, MIC, NYHA, QOL, SGLT2i, AZU1, DD, FPG, Gal-4, IL2RA, KEGG, LAVI, LVH, LVMI, MMP9, MPO, MPP, OPN, ST2, TIMP4, ACS, ADM, AKI, Ang-2, ALDOB, B2MG, BNP, cDPP3, CRP, CS, FGF23, Gal-3, I-FABP, IC1, IL-6, KIM-1, L-FABP, MCS, P-NGAL, P-PENK, PCT, proANP, sST2, suPAR
• Cardiology, Biomarker, Adiposity, Prognosis, Diabetes, Epidemiology, Hormone, Regulation / control
• https://doi.org…LURE.122.009526
• https://doi.org…467-024-45452-3
• https://doi.org…pen-2024-089562
• https://doi.org….1002/ejhf.3502
• https://doi.org….1002/ejhf.3531
• https://doi.org…LURE.125.013166