There are multiple definitions:

1. geographic atrophy circularity index(English)

   • based on GA lesion perimeter and deviation from circularity
   • GA, AMD, RPE, LLVA
   • Ophthalmology, Pathology
   • https://doi.org…tha.2017.08.038

2. generalized arterial calcification of infancy(English)

   • a heritable ectopic mineralization disorder resulting in diffuse arterial calcifications and/or stenosis, mostly caused by mutations in the ENPP1 gene
   • ENPP1
   • Vascular disease, Pediatrics, Congenital disorders
   • https://doi.org…2887-018-1198-4