eIF3

eukaryotic initiation factor 3(English)

  • an approximately 750 kDa complex that controls assembly of 40S ribosomal subunits on messenger RNAs bearing either a 5'-cap or an internal ribosome entry site. Cryo-electron microscopy reconstructions show that eIF3, a five-lobed particle, interacts with the hepatitis C virus
  • HCV, IRES, mRNA
  • Liver disease
  • https://doi.org…science.1118977