B-ALL

B-progenitor acute lymphoblastic leukemia(English)

  • genomic studies have identified chromosomal rearrangements defining new subtypes of B-progenitor acute lymphoblastic leukemia. A revised taxonomy of B-ALL incorporating 23 subtypes defined by chromosomal rearrangements, sequence mutations or heterogeneous genomic alterations, many of which show marked variation in prevalence according to age. Two subtypes have frequent alterations of the B lymphoid transcription-factor gene PAX5
  • PAX5, ALL
  • Genomics
  • https://doi.org…1588-018-0315-5